The first time I switched pain relievers, it was from aspirin to Tylenol. Then recently, I switched again from Tylenol acetaminophen to Advil. You see, I got these really pounding headaches and I found Tylenol didn't always get rid of all the pain. So I tried Advil and found that for my really tough headaches, two Advil work better than two extra-strength Tylenol tablets, better than extra-strength Tylenol caplets, better than Tylenol gel caps. For my tough headaches, Advil just works better. Advil. Advanced medicine for pain.