You might be confused by all the different types of pain relievers and all their claims, but your doctor isn't. They call one type NSAIDs, like aspirin, ibuprofen, and the latest pain reliever called Aleve with naproxen sodium. The pain reliever in Tylenol is different from all these, especially when it comes to your stomach. To varying degrees, every NSAID brand can sometimes cause a side effect of stomach irritation. Tylenol won't. The choice is clear. Tylenol, the pain reliever hospitals use most.